The Serbian has decided to go with Daniel-Kofi Kyereh, while Joseph Paintsil, who was impressive on Monday against Morocco, starts on the bench.
Kyereh has been in great form at club level this season, scoring five goals and assisting nine for St Pauli who are battling for promotion to the Bundesliga.
Ghanasoccernet.com understands Kyereh has been impressive in training and Rajevac trusts him to deliver in Friday’s must-win game.
The backline is unchanged with goalkeeper Jojo Wollacott, defenders Baba Rahman, Andy Yiadom, Daniel Amartey and Alexander Djiku all starting.
However, Djiku must avoid a yellow card which will rule him out of the final group game, having picked up a booking in the first match.
Thomas Partey and Baba Iddrisu have been tasked to control things in the middle of the park.
Captain Andre Ayew, Kamaldeen Sulemana, Jordan Ayew and Kamaldeen Sulemana complete the lineup.
Ghana need a win to stand chance of progressing from the group. A win for Gabon will see them through to the next round.